北海道大学大学院医学研究院 呼吸器内科学教室 北海道大学病院 呼吸器内科 Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University

研究業績

業績

2019年 研究業績

原著論文
  1. Ait Bamai Y, Bastiaensen M, Araki A, Goudarzi H, Konno S, Ito S, Miyashita C, Yao Y, Covaci A, Kishi R: “Multiple exposures to organophosphate flame retardants alter urinary oxidative stress biomarkers among children”, Environ Int. 131:105003.（2019） PubMedへ
  2. Asahina H, Oizumi S, Takamura K, Harada T, Harada M, Yokouchi H, Kenya Kanazawa K, Yuka Fujita Y, Kojima T, Fumiko Sugaya F, Tanaka H, Honda R, Kikuchi E, Ikaria T, Ogi T, Shimizu K, Suzuki M, Konno S, Dosaka-Akitak H, Isobe H, Nishimura M, on behalf of the Hokkaido Lung Cancer Clinical Study Group: “A prospective phase II study of carboplatin and nab-paclitaxel in patients with advanced non-small cell lung cancer and concomitant interstitial lung disease (HOT1302)”, Lung Cancer, 138:65-71(2019) PubMedへ
  3. Becker JH, Gao Y, Soucheray M, Pulido I, Kikuchi E, Rodríguez ML, Gandhi R Lafuente-Sanchis A, Aupí M, Alcácer Fernández-Coronado J, Martín-Martorell P, Cremades A, Galbis-Caravajal JM, Alcácer J,Christensen CL, Simms P, Hess A, Asahina H, Kahle MP, Al-Shahrour F, Borgia JA, Lahoz A, Insa A, Juan O, Jänne PA, Wong KK, Carretero J, Shimamura T: “CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCL”, Cancer Res, 79(17):4439-4452(2019) PubMedへ
  4. Furuta M, Kikuchi H, Shoji T, Takashima Y, Kikuchi E, Kikuchi J, Kinoshita I, Dosaka-Akita H, Sakakibara-Konishi J: “DLL3 regulates the migration and invasion of small cell lung cancer by modulating Snail”, Cancer Sci, 110(5):1599-1608(2019) PubMedへ
  5. Furuta M, Sakakibara-Konishi J, Kikuchi H, Yokouchi H, Nishihara H, Minemura H, Harada M, Yamazaki S, Akie K, Fujita Y, Takamura K, Kojima T, Harada T, Minami Y, Watanabe N, Oizumi S, Suzuki H, Nishimura M, Dosaka-Akita H, Isobe H: “Analysis of DLL3 and ASCL1 in Surgically Resected Small Cell Lung Cancer (HOT1702)”, Oncologist, 24(11): e1172-e1179(2019) PubMedへ
  6. Furuya S, Naya M, Manabe O, Hirata K, Ohira H, Aikawa T, Koyanagawa K, Magota K, Tsujino I, Anzai T, Kuge Y, Oyama-Manabe N, Kudo K, Shiga T, Tamaki N: “18F-FMISO PET/CT detects hypoxic lesions of cardiac and extra-cardiac involvement in patients with sarcoidosis”, J Nucl Cardiol, in press(2019) PubMedへ
  7. Goudarzi H, Konno S, Kimura H, Makita H, Matsumoto M, Takei N, Kimura H, Shimizu K, Suzuki M, Ito YM, Nishimura M, Hi-CARAT investigators: “Impact of abdominal visceral obesity on adult asthma symptoms”, J Allergy Clin Immunol Pract, 7(4): 1222-1229(2019) PubMedへ
  8. Kanazawa J, Kitazawa H, Masuko H, Yatagai Y, Sakamoto T, Kaneko Y, Iijima H, Naito T, Saito T, Noguchi E, Konno S, Nishimura M, Hirota T, Tamari M, Hizawa N: A cis-eQTL allele regulating reduced expression of CHI3L1 is associated with late-onset adult asthma in Japanese cohorts. BMC Med Genet. 20(1):58.doi:10.1186（2019） PubMedへ
  9. Koyanagawa K, Naya M, Aikawa T, Manabe O, Furuya S, Kuzume, M, Oyama-Manabe N, Ohira H, Tsujino I, Anzai T: “The rate of myocardial perfusion recovery after steroid therapy and its implication for cardiac events in cardiac sarcoidosis and primarily preserved left ventricular ejection fraction.”, J Nucl Cardiol, in press (2019) PubMedへ
  10. Koyanagawa K, Naya M, Aikawa T, Manabe O, Kuzume M, Ohira H, Tsujino I, Anzai T: “Prognostic value of phase analysis on gated single photon emission computed tomography in patients with cardiac sarcoidosis”, J Nucl Cardiol, doi: 10.1007/s12350-019-01660-9(2019) PubMedへ
  11. Manabe O, Ohira H, Hirata K, Hayashi S, Naya M, Tsujino I, Aikawa T, Koyanagawa K, Oyama-Manabe N, Tomiyama Y, Magota K, Yoshinaga K, Tamaki N: “Use of 18F-FDG PET/CT texture analysis to diagnose cardiac sarcoidosis”, Eur J Nucl Med Mol Imaging, 46:1240-1247(2019) PubMedへ
  12. Mizugaki H, Hamada A, Shibata T, Hosoda F, Nakamura H, Okuma Y,　Shukuya T, Uemura S, Horiike A, Fukui T, Kogure Y, Daga H, Urata Y, Yamada K, Saeki S, Fujisaka Y, Nakamura Y, Sato M, Yoshida T, Hotta T, Oizumi S, Fujiwara Y, Ohe Y, Fujiwara Y: “Exploration of germline variants responsible for adverse events of crizotinib in anaplastic lymphoma kinase-positive non-small cell lung cancer by target-gene panel sequencing, Lung Cancer, 128:20-25(2019) PubMedへ
  13. Nagaoka K, Yamashita Y ,Kimura H, Kimura H, Suzuki M, Fukumoto T, Hayasaka K , Yoshida M, Hara T, Ohkawa T, Konno S: “Anti-PcrV titers in non-cystic fibrosis with Pseudomonas aeruginosa respiratory tract infection”, Int J Infect Dis, 87: 54-59(2019) PubMedへ
  14. Nagaoka K, Yamashita Y, Kimura H, Suzuki M, Konno S, Fukumoto T, Akizawa K, Morinaga Y, Yanagihara K, Nishimura M : “Effects of anaerobic culturing on pathogenicity and virulence-related gene-expression in pneumococcal pneumonia”, J Infect Dis, 219(10): 1545-1553(2019) PubMedへ
  15. Ninagawa K, Kato M, Nakamura H, Abe N, Kono M, Fujieda Y, Oku K, Yasuda S, Ohira H, Tsujino I, Atsumi T: “Reduced diffusing capacity for carbon monoxide predicts borderline pulmonary arterial pressure in patients with systemic sclerosis”, Rheumatol Int, 39(11): 1883-1887(2019) PubMedへ
  16. Saito Y, Kobayashi M, Yamada T, Sakakibara-Konishi J, Shinagawa N, Kinoshita I, Dosaka-Akita H, Iseki K: “Efficacy of additional dexamethasone administration for the attenuation of paclitaxel-associated acute pain syndrome”, Support Care Cancer, in press 2019 PubMedへ
  17. Saito Y, Yamada T, Kobayashi M, Sakakibara-Konishi J, Shinagawa N, Kinoshita I, Dosaka-Akita H, Iseki K: “Paclitaxel-associated Acute Pain Syndrome Similarly Occurs in the Patients with or without Previously Administered Non-steroidal Anti-inflammatory Drugs Prior to Paclitaxel Administration”, Yakugaku Zasshi , 139(12):1601-1608(2019) PubMedへ
  18. Seyama K, Nukiwa T, Sato T, Suzuki M, Konno S, Takahashi K, Nishimura M, Steinmann K, Sorrells S, Chen J, Hayashi K: “Safety and pharmacokinetics of Alpha-1 MP (Prolastin®-C) in Japanese patients with alpha1-antitrypsin (AAT) deficiency”, Respir Investig, 57(1):89-96(2019) PubMedへ
  19. Shoji T, Konno S, Niida Y, Ogi T, Suzuki M, Shimizu K, Hida Y, Kaga K, Seyama K, Naka T, Matsuno Y, Nishimura M: “Familial multifocal micronodular pneumocyte hyperplasia with a novel splicing mutation in TSC1: Three cases in one family”, PLoS One, 14(2): e0212370(2019) PubMedへ
  20. Suzuki M, Makita H, Konno S, Shimizu K, Nasuhara Y, Nagai K, Akiyama Y, Fuke S, Saito H, Igarashi T, Takeyabu K, Nishimura M: “Annual change in FEV1 in elderly 10-year survivors with established chronic obstructive pulmonary disease”, Sci Rep,9(1):2073(2019) PubMedへ
  21. Takashima Y, Kikuchi E, Kikuchi J, Suzuki M, Kikuchi H, Maeda M, Shoji T, Furuta M, Kinoshita I, Dosaka-Akita H, Sakakibara-Konishi J, Konno S: “Bromodomain and Extraterminal Domain Inhibition Synergizes with WEE1-Inhibitor AZD1775 Effect by Impairing Non-Homologous End Joining and Enhancing DNA Damage in Non-Small Cell Lung Cancer”, Int J Cancer, 146(4):1114-1124(2019) PubMedへ
  22. Takei N, Suzuki M, Makita H, Konno S, Shimizu K, Kimura H, Kimura H, Nishimura M: “Serum alpha-1 antitrypsin levels and the clinical course of chronic obstructive pulmonary disease”, Int J Chron Obstruc Pulmon Dis, 14: 2885-2893(2019) PubMedへ
  23. Tazawa R, Ueda T, Abe M, Tatsumi K, Eda R, Kondoh S, Morimoto K, Tanaka T, Yamaguchi E, Takahashi A , Oda M, Ishii H, Izumi S, Sugiyama H, Nakagawa A, Tomii K, Suzuki M, Konno S, Ohkouchi S, Tode N, Handa T, Hirai T, Inoue Y, Arai T, Asakawa K, Sakagami T, Hashimoto A, Tanaka T, Takada T, Mikami A, Kitamura N, Nakata K: “Inhaled GM-CSF for pulmonary alveolar proteinosis”, N Engl J Med, 381(10): 923-932(2019) PubMedへ
  24. Togo R, Hirata K, Manabe O, Ohira H, Tsujino I, Magota K, Ogawa T, Haseyama M, Shiga T: “Cardiac Sarcoidosis Classification With Deep Convolutional Neural Network-Based Features Using Polar Maps”, Comput Biol Med,104:81-86(2019) PubMedへ
  25. Watanabe S, Inoue T, Okamoto S, Magota K, Takayanagi A, Sakakibara-Konishi J, Katoh N, Hirata K, Manabe O, Toyonaga T, Kuge Y, Shirato H, Tamaki N, Shiga T: “Combination of FDG-PET and FMISO-PET as a treatment strategy for patients undergoing early-stage NSCLC stereotactic radiotherapy”, EJNMMI Res, 9(1):104. doi: 10.1186/s13550-019-0578-6(2019) PubMedへ
  26. Yamashita Y, Nagaoka K, Kimura H , Suzuki M, Konno S, Fukumoto T, Akizawa K, Kaku N, Morinaga Y, Yanagihara K: “Efficacy of azithromycin in a mouse pneumonia model against hospital-acquired methicillin-resistant Staphylococcus aureus”, Antimicrob Agents Chemother, 63(9):e00149-19(2019) PubMedへ
症例報告
  1. Konno S, Matsuno Y, Ichimiya S, Nishimura M, Kawakami Y: Retroperitoneal fibrosis diagnosed as IgG4-related disease after 35 years. Intern Med. 58(4):609-613(2019) PubMedへ
  2. Matsumoto M, Nagaoka K, Suzuki M, Konno S, Takahashi K, Takashina T, Ishiguro N, Nishimura M: “An adult case of severe life-threatning Mycoplasma pneumoniae pneumonia due to a macrolide-resistant strain, Japan: a case report”, BMC Infect Dis, 19(1):204(2019) PubMedへ
  3. Sato k, Ohira H, Horinouchi T, Nakaya T, Sugimoto A, Watanabe T, Tsujino I, Nishimura M: “Chinese herbal medicine Qing-Dai-induced pulmonary arterial hypertension in a patient with ulcerative colitis: A case report and experimental investigation.”, Respir Med Case Rep, 26:265-269(2019) PubMedへ
  4. Takahashi K, Nakamura J, Sakiyama S, Nakaya T, Sato T, Watanabe T, Ohira H, Makita K, Tomaru U, Ishizu A, Tsujino I: “A histopathological report of a 16-year-old male with peripheral pulmonary artery stenosis and Moyamoya disease with a homozygous RNF213 mutation”, Respir Med Case Rep, 29(2019) PubMedへ
  5. 古田 恵，榊原 純，荻 喬博，阿部智絵，北井秀典，清水薫子，朝比奈肇，品川尚文，大泉聡史， 西村正治：「気管食道瘻を呈したEGFR 遺伝子変異陽性肺腺癌に対してゲフィチニブの胃管投与が有効であった1 例」，『気管支学』，41:55-60(2019)
総説・解説・その他
  1. Shinagawa N: “A review of existing and new methods of bronchoscopic diagnosis of lung cancer.” Respir investing, 57(1):3-8(2019) PubMedへ
  2. 今野　哲：「ライフスタイルが喘息病態に及ぼす影響―喫煙，肥満―」，『Pharma Medica』，37(3):29-32((2019)
  3. 鈴木　雅，今野　哲：「好酸球性気道炎症とCOPD　フェノタイプか，喘息合併か」，『呼吸器ジャーナル』，67(2):270-275(2019)
  4. 清水薫子：「気管支喘息」，『呼吸器内科』，35(5):380-386(2019)
  5. 清水薫子，西村正治：「特集：肺高血圧症　Ⅱ.肺高血圧症の診断　呼吸機能検査」，『日本臨床』，77(7):1088-1094(2019)
  6. 福居嘉信，今野　哲：「喘息とCOPDの接点」，『Modrern Physician』，39(8):726-728(2019)
著書
  1. Nizar NJ, Konno S: Mechanisms underlying fixed airflow obstruction and exacerbations. ERS monograph 84:82-92(2019）