北海道大学大学院医学研究院 呼吸器内科学教室 北海道大学病院 呼吸器内科 Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University

研究業績

業績

H27 研究業績

原著論文
  1. Konno S, Taniguchi N, Makita H, Nakamaru Y, Shimizu K, Shijubo N, Fuke S, Takeyabu K, Oguri M, Kimura H, Maeda Y, Suzuki M, Nagai K, Ito YM, Wenzel SE, Nishimura M, Hi-CARAT Investigators. :"Distinct Phenotypes of Cigarette Smokers Identified by Cluster Analysis of Patients with Severe Asthma", Ann Am Thorac Soc, 12(12): 1771-1780 (2015) PubMedへ
  2. 今野　哲：「喫煙と成人喘息, COPD」，『アレルギー』，64(8)：1127-1134 (2015)
  3. Ohira H, deKemp R, Pena E, Davies RA, Stewart DJ, Chandy G, Contreras-Dominguez V, Dennie C, Mc Ardle B, Mc Klein R, Renaud JM, DaSilva JN, Pugliese C, Dunne R, Beanlands R, Mielniczuk LM. :"Shifts in myocardial fatty acid and glucose metabolism in pulmonary arterial hypertension: a potential mechanism for a maladaptive right ventricular response", Eur Heart J Cardiovasc Imaging, doi:10.1093/ehjci/jev136 (2015) PubMedへ
  4. Ohira H, Beanlands R, Chow B. :”The Cardiac Imaging Fellowship Training Program at the University of Ottawa Heart Institute”, Ann Nucl Cardiol, 1(1): 103-105 (2015)
  5. 伊佐田　朗，今野　哲，服部　健史，清水　薫子，清水　健一，谷口　菜津子，檜澤　伸之，西村　正治：「各種感染症抗体価の年齢別陽性率、及びアトピー素因、気管支喘息，アレルギー性鼻炎との関連－北海道上士幌住民における検討―」，『職業・環境アレルギー誌』，22(2)：65-72(2015)
  6. Shimizu K, Makita H, Hasegawa M, Kimura H, Fuke S, Nagai K, Yoshida T, Suzuki M, Konno S, Ito YM, Nishimura M.　:"Regional bronchodilator response assessed by computed tomography in chronic obstructive pulmonary disease", Eur J Radiol, 84(6):1196-1201 (2015) PubMedへ
  7. Mizugaki H, Yamamoto N Nokihara H, Fujiwara Y, Horinouchi H, Kanda S, Kitazono S, Yagishita S, Xiong H, Qian J, Hashiba H, Shepherd SP, Giranda V, Tamura T. :"A phase 1 study evaluating the pharmacokinetics and preliminary efficacy of veliparib (ABT-888) in combination with carboplatin/paclitaxel in Japanese subjects with non-small cell lung cancer (NSCLC)", Cancer Chemother Pharmacol, 76(5):1063-1072 (2015) PubMedへ
  8. Mizugaki H, Yamamoto N, Fujiwara Y, Nokihara H, Yamada Y, Tamura T. :"Current Status of Single-Agent Phase I Trials in Japan: Toward Globalization", J Clin Oncol, 33(18):2051-2061 (2015) PubMedへ
  9. 池澤靖元，榊原　純，庄司哲明，高島雄太，森本　恵，菊地　創，高階太一，大泉　聡史，辻野一三，西村正治：「静脈血栓塞栓症合併肺癌症例の血栓治療に関する検討」，『肺癌』，55(6)：1001-1007 (2015)
  10. Kimura H, Konno S, Isada A, Maeda Y, Musashi M, Nishimura M. :"Contrasting associations of body mass index and measles with asthma and rhinitis in young adults", Allergy Asthma Proc, 36(4):293-299 (2015) PubMedへ
  11. 菊池　創，朝比奈　肇，榊原　純，品川　尚文，大泉　聡史，樋田　泰浩，加賀　基知三，井上　哲也，加藤　徳雄，西村　正治：｢当院における悪性胸膜中皮腫27例の検討｣，『肺癌』，55(1)：2-8 (2015)
  12. Nakamichi S, Nokihara H, Yamamoto N, Yamada Y, Fujiwara Y, Tamura Y, Wakui H, Honda K, Mizugaki H, Kitazono S, Tanabe Y, Asahina H, Yamazaki N, Suzuki S, Matsuoka M, Ogita Y, Tamura T. :"Phase I and pharmacokinetics/pharmacodynamics study of the MEK inhibitor RO4987655 in Japanese patients with advanced solid tumors", Invest New Drugs, 33(3):641-651 (2015) PubMedへ
  13. Sakushima K, Mishina H, Fukuhara S, Sada K, Koizumi J, Sugioka T, Kobayashi N, Nishimura M, Mori J, Makino H, Feldman MD. :"Mentoring the next generation of physician-scientists in Japan: a cross-sectional survey of mentees in six academic medical centers", BMC Med Educ, 19;15:54 (2015) PubMedへ
  14. Sugawara S, Oizumi S, Minato K, Harada T, Inoue A, Fujita Y, Maemondo M, Yoshizawa H, Ito K, Gemma A, Nishitsuji M, Harada M, Isobe H, Kinoshita I, Morita S, Kobayashi K, Hagiwara K, Kurihara M, Nukiwa T; North East Japan Study Group and Tokyo Cooperative Oncology Group. :"Randomized phase II study of concurrent versus sequential alternating gefitinib and chemotherapy in previously untreated non-small cell lung cancer with sensitive EGFR mutations: NEJ005/TCOG0902", Ann Oncol, 26(5):888-894 (2015) PubMedへ
  15. Sze MA, Dimitriu PA, Suzuki M, McDonough JE, Campbell JD, Brothers JF, Erb-Downward JR, Huffnagle GB, Hayashi S, Elliott WM, Cooper J, Sin DD, Lenburg ME, Spira A, Mohn WW, Hogg JC. :"Host Response to the Lung Microbiome in Chronic Obstructive Pulmonary Disease", Am J Respir Crit Care Med, 192(4):438-445 (2015) PubMedへ
  16. Tanabe N, Taniguchi H, Tsujino I, Sakamaki F, Emoto N, Kimura H, Takamura K, Hanaoka M, Nishimura M, Tatsumi K; JRS Lung Disease PH Study Group. :"Multi-institutional retrospective cohort study of patients with severe pulmonary hypertension associated with respiratory diseases", Respirology, 20(5):805-812 (2015) PubMedへ
  17. Xu C, Buczkowski KA, Zhang Y, Asahina H, Beauchamp EM, Terai H, Li YY, Meyerson M, Wong KK, Hammerman PS. :"NSCLC Driven by DDR2 Mutation Is Sensitive to Dasatinib and JQ1 Combination Therapy", Mol Cancer Ther, 14(10):2382-2389 (2015) PubMedへ
  18. Ahmadi A, Ohira H, Mielniczuk LM. :“FDG PET Imaging for Identifying Pulmonary Hypertension and Right Heart Failure”, Curr Cardiol Rep;17(1):555 (2015) PubMedへ
  19. Yokouchi H, Ishida T, Yamazaki S, Kikuchi H, Oizumi S, Uramoto H, Tanaka F, Harada M, Akie K, Sugaya F, Fujita Y, Fukuhara T, Takamura K, Kojima T, Harada T, Higuchi M, Matsuura Y, Honjo O, Minami Y, Watanabe N, Nishihara H, Suzuki H, Dosaka-Akita H, Isobe H, Nishimura M, Munakata M. :"Prognostic impact of clinical variables on surgically resected small-cell lung cancer: Results of a retrospective multicenter analysis", Lung Cancer, 90(3):548-553 (2015) PubMedへ
  20. Nagai K, Makita H, Suzuki M, Shimizu K, Konno S, Ito YM, Nishimura M. :"Differential changes in quality of life components over 5 years in chronic obstructive pulmonary disease patients", Dove press, 10(1):745-757 (2015) PubMedへ
  21. 宇尾　基弘，和田　敬広，杉山　知子，中野　郁夫，木村　清延，谷口　菜津子，猪又　崇志，今野　哲，西村　正治：「放射光XRF およびXAFS を用いた超硬合金肺病理標本中の元素分析」，『Ｘ線分析の進歩』，46：177-186（2015）
症例発表
  1. Kitai H, Sakakibara-Konishi J, Oizumi S, Hirohashi Y, Saito W, Kanda A, Sato N, Nishimura M. :"Spontaneous regression of small cell lung cancer combined with cancer associated retinopathy", Lung Cancer, 87(1):73-6 (2015) PubMedへ
  2. Terui H, Konno S, Kaga K, Matsuno Y, Hatanaka C K, Kanno H, Moriyama H, Uo M, Nishimura M. :"Two cases of hard metal lung disease showing gradual improvement in pulmonary function after avoiding dust exposure", Journal of Occupational Medicine and Toxicology, 4;10:29 (2015) PubMedへ
総説・解説・その他
  1. 大泉聡史：「EGFR遺伝子変異陽性肺癌の治療」，『THE LUNG perspectives』，23（1）：24-28（2015）
  2. 大泉聡史：｢EGFR遺伝子変異陽性の非小細胞肺癌におけるEGFR-TKIとプラチナ療法の併用の治療戦略｣，『肺癌』，55(6)：871-878(2015)
  3. 大泉聡史：「NEJ005/TCOG0902試験からみえてくるもの」，『分子呼吸器病』，19（1）：64-66(2015)
  4. 今野　哲：「気管支喘息診療に残された課題-難治性喘息の克服に向けて-」，『日本臨床皮膚科医会雑誌』，32(5)：563-565(2015)
  5. Ohira H, Beanlands RS, Davies RA, Mielniczuk L. :“The role of nuclear imaging in pulmonary hypertension”, J Nucl Cardiol, 22(1): 141-57 (2015) PubMedへ
  6. 大平　洋：「肺高血圧症診療に心エコーを役立てる」，『医学のあゆみ』，255(1)：29-34(2015)
  7. 鈴木　雅，西村正治：「病態に関する最近の話題」，『日本内科学会雑誌』，104（6）：1074-1081（2015）
  8. 鈴木　雅，猪又崇志，西村正治：｢COPDの病因・発症機序等を踏まえた予防戦略｣，『進めよう！COPD対策』，79(12)：829-834(2015)
  9. Inomata T, Konno S, Azuma A. :"Historical transition of management of sarcoidosis", World Journal of Respirology, 5(1):4-16 (2015)
  10. Kimura H, Suzuki M, Konno S, Nishimura M, Bobolea I, Barranco P, Del Pozo V, Romero D, Sanz V, López-Carrasco V, Canabal J, Villasante C, Quirce S. :"Sputum periostin in patients with different severe asthma phenotypes", Allergy, 70(7):884-885 (2015) PubMedへ
著書
  1. 西村正治：「肺高血圧症患者の酸素療法を含めた全身管理の注意点を教えてください」,『～早期診断・治療のための～肺高血圧症　Q&A』， 【先端医学社・東京・福田恵一　編】，207-210(2015)
  2. 西村正治：「慢性閉塞性肺疾患（COPD）Chronic Obstructive Pulmonary Disease」，『今日の診断指針　第７版』，【医学書院・東京・金澤一郎，永井良三　編】，999-1002(2015)
  3. Suzuki M, Nishimura M: 「Diagnosis of COPD」, 『100 Key Questions on Chronic Obstructive Pulmonary Disease (COPD)』, 【PERMANYER・Spain・EDITORS: CHRISTINE JENKINS, MARC MIRAVITLLES】, 21-28(2015)
  4. 清水薫子，長岡健太郎，西村正治：「Chapter1.呼吸器疾患」，『内科外来処方navi』，【中外医学社・東京・富野康日己　編】，1-10(2015)