北海道大学大学院医学研究院 呼吸器内科学教室 北海道大学病院 呼吸器内科 Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University

研究業績

業績

H28 研究業績

原著論文
  1. Hamada T, Komatsu H, Rosenzweig MQ, Chohnabayashi N, Nishimura N, Oizumi S, Ren D:" Impact of Symptom Clusters on Quality of Life Outcomes in Patients from Japan with Advanced Nonsmall Cell Lung Cancers", Asia Pac J Oncol Nurs, 3(4):370-381(2016) PubMedへ
  2. Ikezawa Y, Sakakibara-Konishi J, Mizugaki H, Oizumi S, Nishimura M:" Inhibition of Notch and HIF enhances the antitumor effect of radiation in Notch expressing lung cancer", Int J Clin Oncol, 22(1):59-69(2017) PubMedへ
  3. Ikezawa Y, Shinagawa N, Sukoh N, Morimoto M, Kikuchi H, Watanabe M, Nakano K, Oizumi S, Nishimura M:" Usefulness of Endobronchial Ultrasonography With a Guide Sheath and Virtual Bronchoscopic Navigation for Ground-Glass Opacity Lesions", Ann Thorac Surg, 103(2):470-475(2017) PubMedへ
  4. Ishiguro N, Oyamada R, Nasuhara Y, Yamada T, Miyamoto T, Imai S, Akizawa K, Fukumoto T, Iwasaki S, Iijima H, Ono K:" Three-day regimen of oseltamivir for postexposure prophylaxis of influenza in wards", J Hosp Infect. 94(2):150-153(2016) PubMedへ
  5. Juneau D, Erthal F, Ohira H, Mc Ardle B, Hessian R, deKemp RA, Beanlands RS:" Clinical PET Myocardial Perfusion Imaging and Flow Quantification", Cardiol Clin, 34(1):69-85(2016) PubMedへ
  6. Kimura H, Konno S, Nakamaru Y, Makita H, Taniguchi N, Shimizu K, Suzuki M, Ono J, Ohta S, Izuhara K, Nishimura M:" Sinus Computed Tomographic Findings in Adult Smokers and Nonsmokers with Asthma Analysis of Clinical Indices and Biomarkers ", Ann Am Thorac Soc, in press PubMedへ
  7. Kitai H, Ebi H, Tomida S, Floros KV, Kotani H, Adachi Y, Oizumi S, Nishimura M, Faber AC, Yano S:" Epithelial-to-Mesenchymal Transition Defines Feedback Activation of Receptor Tyrosine Kinase Signaling Induced by MEK Inhibition in KRAS-Mutant Lung Cancer", Cancer Discov, 6(7):754-769(2016) PubMedへ
  8. Koyama S, Akbay EA, Li YY, Aref AR, Skoulidis F, Herter-Sprie GS, Buczkowski KA, Liu Y, Awad MM, Denning WL, Diao L, Wang J, Parra-Cuentas ER, Wistuba II, Soucheray M, Thai T, Asahina H, Kitajima S, Altabef A, Cavanaugh JD, Rhee K, Gao P, Zhang H, Fecci PE, Shimamura T, Hellmann MD, Heymach JV, Hodi FS, Freeman GJ, Barbie DA, Dranoff G, Hammerman PS, Wong KK:" STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment", Cancer Res, 76(5):999-1008(2016) PubMedへ
  9. Koyama S, Akbay EA, Li YY, Herter-Sprie GS, Buczkowski KA, Richards WG, Gandhi L, Redig AJ, Rodig SJ, Asahina H, Jones RE, Kulkarni MM, Kuraguchi M, Palakurthi S, Fecci PE, Johnson BE, Janne PA, Engelman JA, Gangadharan SP, Costa DB, Freeman GJ, Bueno R, Hodi FS, Dranoff G, Wong KK, Hammerman PS:" Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints", Nat Commun, 7:10501(2016) PubMedへ
  10. Kubota N, Kubota T, Kajiwara E, Iwamura T, Kumagai H, Watanabe T, Inoue M, Takamoto I, Sasako T, Kumagai K, Kohjima M, Nakamuta M, Moroi M, Sugi K, Noda T, Terauchi Y, Ueki K, Kadowaki T:" Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity", Nat Commun, 7:12977-93 (2016) PubMedへ
  11. Manabe O, Yoshinaga K, Ohira H, Masuda A, Sato T, Tsujino I, Yamada A, Oyama-Manabe N, Hirata K, Nishimura M, Tamaki N:" The effects of 18-h fasting with low-carbohydrate diet preparation on suppressed physiological myocardial (18)F-fluorodeoxyglucose (FDG) uptake and possible minimal effects of unfractionated heparin use in patients with suspected cardiac involvement sarcoidosis", J Nucl Cardiol, 23(2):244-252(2016) PubMedへ
  12. Mizugaki H, Yamamoto N, Murakami H, Kenmotsu H, Fujiwara Y, Ishida Y, Kawakami T, Takahashi T:" Phase I dose-finding study of monotherapy with atezolizumab, an engineered immunoglobulin monoclonal antibody targeting PD-L1, in Japanese patients with advanced solid tumors", Investigational New Drugs, 34(5):596-603(2016) PubMedへ
  13. Naka T, Hatanaka Y, Marukawa K, Okada H, Hatanaka C, Sakakibara-Konishi J, Oizumi S, Hida Y, Kaga K, Mitsuhashi T, Matsuno Y:" Comparative genetic analysis of a rare synchronous collision tumor composed of maliganant pleural mesothelioma and promary pulmonary adenocarcinoma", Diagn Pathol, 11:38(2016) PubMedへ
  14. Noguchi A, Kato M, Kono M, Ohmura K, Ohira H Tsujino I, Oyama-Manabe N, Oku K, Bohgaki T, Horita T, Yasuda S, Nishimura M, Atsumi T:" Bi-ventricular interplay in patients with systemic sclerosis-associated pulmonary arterial hypertension: Detection by cardiac magnetic resonance", Mod Rheumatol, 18：1-8(2016) PubMedへ
  15. Ohira H, Birnie DH, Pena E, Bernick J, Mc Ardle B, Leung E, Wells GA, Yoshinaga K, Tsujino I, Sato T, Manabe O, Oyama-Manabe N, Nishimura M, Tamaki N, Dick A, Dennie C, Klein R, Renaud J, deKemp RA, Ruddy TD, Chow BJ, Davies R, Hessian R, Liu P, Beanlands RS, Nery PB:" Comparison of (18)F-fluorodeoxyglucose positron emission tomography (FDG PET) and cardiac magnetic resonance (CMR) in corticosteroid-naive patients with conduction system disease due to cardiac sarcoidosis", Eur J Nucl Med Mol Imaging, 43(2):259-269(2016) PubMedへ
  16. Ohira H, Promislow S, Clarkin O, Ruddy TD, Beanlands RB, Chow BJ:" How to Write a Good Myocardial Perfusion Imaging Report: Current North American Reports", Annals of Nuclear Cardiology, 2(1):162-166(2016) Pdfへ
  17. Sakakibara-Konishi J, Ikezawa Y, Oizumi S, Kikuchi J, Kikuchi E, Mizugaki H, Kinoshita I, Dosaka-Akita H, Nishimura M:" Combined antitumor effect of γ-secretase inhibitor and ABT-737 in Notch-expressing non-small cell lung cancer", International Journal of Clinical Oncology, 22(2):257-268(2016) PubMedへ
  18. Sato T, Tsujino I, Sugimoto A, Nakaya T, Watanabe T, Ohira H, Suzuki M, Konno S, Oyama-Manabe N, Nishimura M:" The effects of pulmonary vasodilating agents on right ventricular parameters in severe group 3 pulmonary hypertension: a pilot study", Pulm Circ, 6(4):524-531(2016) PubMedへ
  19. Shimizu K, Seto R, Makita H, Suzuki M, Konno S, Ito YM, Kanda R, Ogawa E, Nakano Y, Nishimura M:" Computed tomography (CT)-assessed bronchodilation induced by inhaled indacaterol and glycopyrronium/indacaterol in COPD", Respir Med, 119:70-77(2016) PubMedへ
  20. Suzuki M, Makita H, Konno S, Shimizu K, Kimura H, Kimura H, Nishimura M:" Asthma-like features and clinical course of chronic obstructive pulmonary disease. An analysis from the Hokkaido COPD cohort study", Am J Respir Crit Care Med, 194(11):1358-1365(2016) PubMedへ
  21. Takada T, Mikami A, Kitamura N, Seyama K, Inoue Y, Nagai K, Suzuki M, Moriyama H, Akasaka K, Tazawa R, Hirai T, Mishima M, Hayashida M, Hirose M, Sugimoto C, Arai T, Hattori N, Watanabe K, Tamada T, Yoshizawa H, Akazawa K, Tanaka T, Yagi K, Young LR, McCormack FX, Nakata K:" Efficacy and Safety of Long-Term Sirolimus Therapy for Asian Patients with Lymphangioleiomyomatosis", Ann Am Thorac Soc, 13(11):1912-1922(2016) PubMedへ
  22. Takashina C, Tsujino I, Watanabe T, Sakaue S, Ikeda D, Yamada A, Sato T, Ohira H, Otsuka Y, Oyama-Manabe N, Ito YM, Nishimura M:" Associations among the plasma amino acid profile, obesity, and glucose metabolism in Japanese adults with normal glucose tolerance", Nutr Metab (Lond), 13:5 (2016) PubMedへ
  23. Takashina T, Kinoshita I, Kikuchi J, Shimizu Y, Sakakibara-Konishi J, Oizumi S, Nishimura M, Dosaka-Akita H:" Combined inhibition of EZH2 and HDACｓ as a potential epigenetic therapy for non-small cell lung cancer cells", Cancer Sci, 107(7):955-962(2016) PubMedへ
  24. Takeuchi Y, Shinagawa N, Kikuchi E, Matsuno Y, Hida Y, Kaga K, Oizumi S, Nishimura M:" The predictive value of endobronchia lultrasonography with a guide sheath in the diagnosis of the histologic subtypes of lung cancer", Respir Investig, 54(6):473-478(2016) PubMedへ
  25. Tamura Y, Nokihara H, Honda K, Tanabe Y, Asahina H, Yamada Y, Enatsu S, Kurek R, Yamamoto N, Tamura T:" Phase I study of the second-generation, recombinant, human EGFR antibody necitumumab in Japanese patients with advanced solid tumors", Cancer Chemother Pharmacol, 78(5):995-1002(2016) PubMedへ
  26. Tsukuda Y, Funakoshi T, Nasuhara Y, Nagano Y, Shimizu C, Iwasaki N:" Venipuncture Nerve Injuries in the Upper Extremity From More Than 1 Million Procedures", Journal of Patient Safety, in press(2016) PubMedへ
  27. Watanabe T, Tsujino I, Konno S, Ito YM, Takashina C, Sato T, Isada A, Ohira H, Ohtsuka Y, Fukutomi Y, Nakamura H, Kawagishi Y, Okada C, Hizawa N, Taniguchi M, Akasawa A, Nishimura M:" Association between Smoking Status and Obesity in a Nationwide Survey of Japanese Adults", PLoS One, 11(3):e0148926 (2016) PubMedへ
  28. Zhang H, Qi J, Reyes JM, Li L, Rao PK, LI F, Lin CY, Perry JA, Lawlor MA, Federation A, De Raedt T, Li YY, Liu Y, Duarte MA, Zhang Y, Herter-Spirie GS, Kikuchi E, Carretero J, Perou CM, Reibel JB, Paulk J, Bronson RT, Watanabe H, Brainson CF, Kim CF, Hammerman PS, Brown M, Cichowski K, Long H, Bradner JE, Wong KK:" Oncogenic Deregulation of EZH2 as an Opportunity for Targeted Therapy in Lung Cancer", Cancer Discov, 6(9):1006-1021(2016) PubMedへ
症例報告
  1. 池澤靖元，水柿秀紀，岡田宏美，大泉聡史，松野吉弘，西村正治：「指尖転移を来した肺扁平上皮癌の1例」，『日本呼吸器学会誌』，5(4)：189-193(2016)
総説・解説・その他
  1. Nishimura M:" Editorial: Similarities and differences between East and West in COPD", Respirology, 21(8):1340-1341 (2016) PubMedへ
  2. 大泉聡史：「抗PD-1/PD-L1抗体による肺がん治療　2016年アップデート」，『肺がん薬物治療2016』，33(6)：4-12(2016)
  3. 鈴木　雅，西村正治：「薬物療法：重症度、フェノタイプに応じた治療選択」，『呼吸器内科』，30(6)：482-486(2016)
  4. 鈴木　雅，牧田比呂仁，今野　哲，清水薫子，木村裕樹，木村孔一，西村正治：「慢性閉塞性肺疾患(COPD)患者における喘息様検査所見と臨床経過との関連：北海道COPDコホート研究より」，『北海道医誌』，91(6)：78(2016)
著書
  1. 大泉聡史：「第3章 EGFRチロシンキナーゼ阻害薬」，『呼吸器疾患–最新の薬物療法–1 悪性腫瘍』，【克誠堂出版・東京，江口研二，川名明彦　編】26-44(2016)
  2. 鈴木　雅，西村正治：「COPDのphenotype」，『呼吸器疾患最新の治療　2016－2018』，【南江堂・東京，杉山幸比古，門田淳一，弦間昭彦　編】，44-48(2016)
  3. 南須原康行，宝金清博：「医療安全」，『脳神経外科学Ⅰ改訂12版』，【金芳堂・京都，太田富雄編】，757-777(2016)