北海道大学大学院医学研究院 呼吸器内科学教室 北海道大学病院 呼吸器内科 Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University

研究業績

業績

2023年 研究業績

原著論文
  1. Abe Y, Suzuki M, Kimura H, Shimizu K, Takei N, Oguma A, Matsumoto-Sasaki M, Goudarzi H, Makita H, Nishimura M, Konno S: “Blood eosinophil count variability in chronic obstructive pulmonary disease and severe asthma”, Allergol Int, 72(3):402-410(2023) PubMedへ
  2. Fujita K, Shoji S, Saito R, Nomura M, Hotta T, Asahina H, Kawakami M, Nakachi I, Hasegawa Y, Okafuji K, Suzuki A, Miyanaga A, Sunaga N, Nagashima H, Ikeda N, Watanabe S, Nagai Y, Furuta M, Kage H, Arai D, Fukuhara T, Nakayama M, Morita S, Kobayashi K, Hagiwara K.: “Detection of multiple druggable mutations of lung cancer from cytology specimens by MINtS: An advanced medicine A trial”, Cancer Sci, 114(8):3342-3351(2023) PubMedへ
  3. Goudarzi H, Ikeda-Araki A, Bamai YA, Ito S, Inao T, Yokota I, Miyashita C, Kishi R, Konno S: “Potential determinants of T helper 2 markers and their distribution in school-aged children”, Allergol Int, 72(1):100-106(2023) PubMedへ
  4. Goudarzi H, Kimura H, Kimura H, Makita H, Takimoto-Sato M, Abe Y, Oguma A, Matsumoto M, Takei N, Matsumoto-Sasaki M, Shimizu K, Suzuki M, Shijubo N, Huang S, Hizawa N, Nishimura M, Konno S: “Association of serum GG16 levels with eosinophilic inflammation and respiratory dysfunction in severe asthma”, Respir med, 206:107089(2023) PubMedへ
  5. Hosokawa K, Abe K, Funakoshi K, Tamura Y, Nakashima N, Todaka K, Taniguchi Y, Inami T, Adachi S, Tsujino I, Yamashita J, Minatsuki S, Ikeda N, Shimokawahara H, Kawakami T, Ogo T, Hatano M, Ogino H, Fukumoto Y, Tanabe N, Matsubara H, Fukuda K, Tatsumi K, Tsutsui H: “Long-term outcome of chronic thromboembolic pulmonary hypertension using direct oral anticoagulants and warfarin: a Japanese prospective cohort study”, J Thromb Haemost, 21(8):2151-2162(2023) PubMedへ
  6. Ikeda S, Ueno Y, Maemura K, Yachi S, Takeyama M, Nishimoto Y, Tsujino I, Nakamura J, Yamamoto N, Nakata H, Umetsu M, Aikawa S, Hayashi H, Satokawa H, Okuno Y, Iwata E, Ogihara Y, Ikeda N, Kondo A, Iwai T, Yamada N, Ogawa T, Kobayashi T, Mo M, Yamashita Y; CLOT-COVID Study Investigators: “Association Between the Development of Thrombosis and Worsening of Disease Severity in Patients With Moderate COVID-19 on Admission - From the CLOT-COVID Study”, Circ J, 87(3):448-455(2023) PubMedへ
  7. Kagami K, Ishiguro N, Iwasaki S, Taki K, Fukumoto T, Hayasaka K, Oyamada R, Watanabe T, Nakakubo S, Niinuma Y, Sugawara M, Takekuma Y: “Correlation between antibiotic use and resistance of gram-negative bacteria at a university hospital in Japan from 2013 to 2021: a study using the Japan Surveillance for Infection Prevention and Healthcare Epidemiology (J-SIPHE) system”, Eur J Hosp Pharm, 12:ejhpharm-2023-003797(2023). PubMedへ
  8. Kagami K, Oyamada R, Watanabe T, Nakakubo S, Hayashi T, Iwasaki S, Fukumoto T, Usami T, Hayasaka K, Fujisawa S: “Factors associated with household transmission of SARS-CoV-2 omicron variant to health care workers: A retrospective cohort study”, Int J Nurs Pract, 29(5): e13195(2023) PubMedへ
  9. Kazui S, Takenaka S, Nagai T, Kato Y, Komoriyama H, Kobayashi Y, Takahashi A, Kamiya K, Sato T, Tada A, Yasui Y, Nakai M, Sato T, Tsujino I, Konno S, Anzai T: “Association of longitudinal cardiac troponin trajectory with adverse events in patients with cardiac sarcoidosis”, Int J Cardiol, 389:131268(2023) PubMedへ
  10. Kuwana M, Abe K, Kinoshita H, Matsubara H, Minatsuki S, Murohara T, Sakao S, Shirai Y, Tahara N, Tsujino I, Takahashi K, Kanda S, Ogo T: “Efficacy, safety, and pharmacokinetics of inhaled treprostinil in Japanese patients with pulmonary arterial hypertension”, Pulm Circ, 13(1):e12198(2023) PubMedへ
  11. Matsumoto M, Kimura H, Shimizu K, Suzuki M, Asakura S, Hashino S, Konno S: “Nine-Year Trend in the Prevalence of Allergic Diseases and Their Associated Factors in Young Adults”, Int Arch Allergy Immunol, 185(3):218-227(2023). PubMedへ PubMedへ
  12. Nakakubo S, Kishida N, Okuda K, Kamada K, Iwama M, Suzuki M, Yokota I, Ito YM, Nasuhara Y, Boucher RC, Konno S: “Associations of COVID-19 symptoms with omicron subvariants BA.2 and BA.5, host status, and clinical outcomes in Japan: a registry-based observational study” Lancet Infect Dis, 23(11):1244-1256(2023) PubMedへ
  13. Nakakubo S, Unoki Y, Kitajima K, Terada M, Gatanaga H, Ohmagari N, Yokota I, Konno S: “Serum Lactate Dehydrogenase Level One Week after Admission Is the Strongest Predictor of Prognosis of COVID-19: A Large Observational Study Using the COVID-19 Registry Japan”, Viruses, 15(3):671(2023) PubMedへ
  14. Nakamura J, Tsujino I, Shima H, Nakaya T, Sugimoto A, Sato T, Watanabe T, Ohira H, Suzuki M, Tsuneta S, Hisada R, Kato M, Konno S: “Clinical and Hemodynamic Responses to Imatinib in Pulmonary Veno-Occlusive Disease/Pulmonary Capillary Hemangiomatosis: A Retrospective Pilot Study of Five Cases and Review of the Literature”, Am J Cardiovasc Drugs, 23(3):329-338(2023) PubMedへ
  15. Nakamura J, Tsujino I, Shima H, Nakaya T, Sugimoto A, Sato T, Watanabe T, Ohira H, Suzuki M, Yokota I, Konno S: “Impact of cancer on the prevalece, management, and outcome of patients with chronic thromboembolic pulmonary hypertension”, J Thromb Thrombolysis, 56(4):588-593(2023) PubMedへ
  16. Ninagawa K, Kato M, Kikuchi Y, Sugimori H, Kono M, Fujieda Y, Tsujino I, Atsumi T: “Predicting the response to pulmonary vasodilator therapy in systemic sclerosis with pulmonary hypertension by using quantitative chest CT”, Mod Rheumatol, 33(4):758-767(2023) PubMedへ
  17. Oda M, Yamaura K, Ishii H, Kitamura N, Tazawa R, Abe M, Tatsumi K, Eda R, Kondoh S, Morimoto K, Tanaka T, Yamaguchi E, Takahashi A, Izumi S, Sugiyama H, Nakagawa A ,Tomii K, Suzuki M, Konno S, Ohkouchi S, Tode N, Handa T, Hirai T, Inoue Y, Arai T, Asakawa K, Tanaka T, Takada T, Nonaka H, Nakata K: “Quantitative Evaluation of Changes in Three-Dimensional CT Density Distributions in Pulmonary Alveolar Proteinosis after GM-CSF Inhalation”, Respiration, 102(2):101-109(2023) PubMedへ
  18. Ogihara Y, Yachi S, Takeyama M, Nishimoto Y, Tsujino I, Nakamura J, Yamamoto N, Nakata H, Ikeda S, Umetsu M, Aikawa S, Hayashi H, Satokawa H, Okuno Y, Iwata E, Ikeda N, Kondo A, Iwai T, Yamada N, Ogawa T, Kobayashi T, Mo M, Yamashita Y; CLOT-COVID Study Investigators: “Influence of obesity on incidence of thrombosis and disease severity in patients with COVID-19: From the CLOT-COVID study”, J Cardiol, 81(1):105-110(2023) PubMedへ
  19. Oguma A, Shimizu K, Kimura H, Tanabe N, Sato S, Yokota I, Takimoto-Sato M, Matsumoto-Sasaki M, Abe Y, Takei N, Goudarzi H, Suzuki M, Makita H, Hirai T, Nishimura M, Konno S; Hi-CARAT investigators: “Differential role of mucus plugs in asthma: Effects of smoking and association with airway inflammation”, Allergol Int, 72:262-270(2023) PubMedへ
  20. Okada N, Yamamoto Y, Oguma T, Tanaka J, Tomomatsu K, Shiraishi Y, Matsuse H, Shimoda T, Kimura H, Watai K, Harada T, Fujita Y, Obase Y, Suzukawa M, Suzuki J, Takayanagi N, Ishiguro T, Masaki K, Fukunaga K, Asano K: “Allergic bronchopulmonary aspergillosis with atopic, nonatopic, and sans asthma-Factor analysis”, Allergy,78(11):2933-2943 (2023) PubMedへ
  21. Saito Y, Kobayashi M, Tmaki S, Nakamura K, Hirate D, Takahashi K, Takekuma Y, Sakakibara-Konishi J, Shimizu Y, Kinoshita I, Sugawara M: “Risk factor analysis for cisplatin-induced nephrotoxicity with the short hydration method in diabetic patients”, Sci Rep, 13(1):17126(2023) PubMedへ
  22. Saito Y, Tamaki S, Hirate D, Takada S, Takahashi K, Takekuma Y, Sakakibara-Konishi J, Shimizu Y, Kinoshita I, Sugawara M: “Detection of factors related to treatment reduction in docetaxel and ramucirumab for non-small cell lung cancer treatment”, Sci Rep, 13(1):19457(2023) PubMedへ
  23. Sato M, Maishi N, Hida Y, Yanaga-Matsuda A, Alam MT, Sakakibara-Konishi J, Nam JM, Onodera Y, Konno S, Hida K: “Angiogenic inhibitor pre-administration improves the therapeutic effects of immunotherapy”, Cancer Med, 12:9760-9773(2023) PubMedへ
  24. Shiiya A, Noguchi T, Tomaru U, Ariga S, Takashima Y, Ohhara Y, Taguchi J, Takeuchi S, Shimizu Y, Kinoshita I, Koizumi T, Matsuno Y, Shinagawa N, Sakakibara-Konishi J, Dosaka-Akita H: “EGFR inhibition in EGFR-mutant lung cancer cells perturbs innate immune signaling pathways in the tumor microenvironment” Cancer Sci ,114(4):1270-1283(2023) PubMedへ
  25. Shima H, Tanabe N, Oguma A, Shimizu K, Kaji S, Terada K, Oguma T, Kubo T, Suzuki M, Makita H, Sato A, Nishimura M, Sato S, Konno S, Hirai T: “Subtyping emphysematous COPD by respiratory volume change distributions on CT”, Thorax, 78(4):344-353(2023) PubMedへ
  26. Shimada T, Chubachi S, Otake S, Sakurai K, Sasaki M, Iijima H, Tanabe N, Tanimura K, Shimizu K, Shirahata T, Suzuki M, Sato S, Nakamura H, Asano K, Fukunaga K: “Differential impacts between fat mass index and fat-free mass index on patients with COPD”, Respir Med, 217:107346(2023) PubMedへ
  27. Shimizu k, Kimura H, Tanabe N, Chubachi S, sato S, Suzuki M, Tanimura K, Iijima H, Oguma A, Ito YM, Wakazono N, Takimoto-Sato M, Matsumoto-Sasaki M, Abe Y, Takei N, Makita H, Nishimura M, Konno S, Hi-CARAT investigators: “Relationships of computed tomography-based small vessel indices of the lungs with ventilation heterogeneity and high transfer coefficients in non-smokers with asthama”,Front Physiol , 14:1137603(2023) PubMedへ
  28. Shiraishi Y, Tanabe N, Shimizu K, Oguma A, Shima H, Sakamoto R, Yamazaki H, Oguma T, Sato A, Suzuki M, Makita H, Muro S, Nishimura M, Sato S, Konno S, Hirai T: “Stronger Associations of Centrilobular Than Paraseptal Emphysema With Longitudinal Changes in Diffusing Capacity and Mortality in COPD”, Chest, 164(2):327-338(2023) PubMedへ
  29. Sugimoto A, Matsumoto S, Udagawa H, Itotani R, Usui Y, Umemura S, Nishino K, Nakachi I, Kuyama S, Daga H, Hara S, Miyamoto S, Kato T, Sakakibara-Konishi J, Tabata E, Nakagawa T, Kawaguchi T, Sakai T, Shibata Y, Izumi H, Zenke Y, Yoh K, Goto K: “A large-scale prospective concordance study of plasma- and tissue-based next-generation targeted sequencing for advanced non-small cell lung cancer (LC-SCRUM-Liquid), Clin Cancer Res, 29:1506-1514(2023) PubMedへ
  30. Suzuki M, Makita H, Konno S, Nishimura M: “Clinical characteristics and natural course of chronic obstructive pulmonary disease and/or asthma in Japanese patients: a summary report of two Hokkaido-based cohort studies”, Respir Investig, 61(4):527-539(2023) PubMedへ
  31. Suzuki M, Matsumoto I, Ishida M, Horie Y, Ban H, Takeuchi W, Nakagawa S, Nakagawa T, Kitamura T, Muro S: “Investigation of time profile of FEV1 across the onset of potential COPD: a retrospective cohort study using medical checkup data in Japan”, Sci Rep, 13(1):5454(2023) PubMedへ
  32. Takahashi H, Sakakibara-Konishi J, Furuta M, Shoji T, Tsuji K, Morinaga D, Kikuchi E, Kikuchi J, Noguchi T, Hatanaka KC, Hatanaka Y, Shinagawa N, Konno S: “Notch pathway regulates osimertinib drug-tolerant persistence in EGFR-mutated non–small-cell lung cancer, Cancer Sci, 114:1635-1650(2023) PubMedへ
  33. Takeyama M, Yachi S, Nishimoto Y, Tsujino I, Nakamura J, Yamamoto N, Nakata H, Ikeda S, Umetsu M, Aikawa S, Hayashi H, Satokawa H, Okuno Y, Iwata E, Ogihara Y, Ikeda N, Kondo A, Iwai T, Yamada N, Ogawa T, Kobayashi T, Mo M, Yamashita Y: “Mortality-associated Risk Factors in Hospitalized COVID-19 Patients in Japan: Findings of the CLOT-COVID Study”, J Epidemiol, 33(3):150-157(2023) PubMedへ
  34. Takimoto-Sato M, Suzuki M, Kimura H, Ge H, Matsumoto M, Makita H, Arai S, Miyazaki T, Nishimura M, Konno S: “Apoptosis inhibitor of macrophage (AIM)/CD5L is involved in the pathogenesis of COPD”,Respir Res,24(1):201(2023) PubMedへ
  35. Tamura Y, Kumamaru H, Nishimura S, Nakajima Y, Matsubara H, Taniguchi Y, Tsujino I, Shigeta A, Kinugawa K, Kimura K, Tatsumi K: “Initial Triple Combination Therapy Including Intravenous Prostaglandin I2 for the Treatment of Patients with Severe Pulmonary Arterial Hypertension”, Int Heart J,64(4):684-692(2023) PubMedへ
  36. Tamura Y, Takeyasu R, Takata T, Miyazaki N, Takemura R, Wada M, Tamura Y, Abe K, Shigeta A, Taniguchi Y, Adachi S, Inami T, Tsujino I, Tahara N, Kuwana M: “SATISFY-JP, a phase II multicenter open-label study on Satralizumab, an anti-IL-6 receptor antibody, use for the treatment of pulmonary arterial hypertension in patients with an immune-responsive-phenotype: Study protocol”, Pulm Circ, 13(2):e12251(2023) PubMedへ
  37. Tamura Y, Tamura Y, Shigeta A, Hosokawa K, Taniguchi Y, Inami T, Adachi S, Tsujino I, Nakanishi N, Sato K, Sakamoto J, Tanabe N, Takama N, Nakamura K, Kubota K, Komura N, Kato S, Yamashita J, Takei M, Joho S, Ishii S, Takemura R, Sugimura K, Tatsumi K: “Adult-onset idiopathic peripheral pulmonary artery stenosis”, Eur Respir J, 62(6):2300763(2023) PubMedへ
  38. Tanabe N, Sato S, Shimada T, Kaji S, Shiraishi Y, Terada S, Maetani T, Mochizuki F, Shimizu K, Suzuki M, Chubachi S, Terada K, Tanimura K, Sakamoto R, Oguma T, Sato A, Kanasaki M, Muro S, Masuda I, Iijima H, Hirai T: “A reference equation for lung volume on computed tomography in Japanese middle-aged and elderly adults”, Respir Investig, 62(1):121-127(2023) PubMedへ
  39. Tsuji K, Kikuchi E, Takashima Y, Shoji T, Takahashi H, Ito S, Morinaga D, Kashima M, Maeda M, Kitai H, Kikuchi J, Sakakibara-Konishi J, Konno S: “Inhibition of non-homologous end joining mitigates paclitaxel resistance resulting from mitotic slippage in non-small cell lung cancer”, Cell Cycle, 22(17):1854-1864(2023) PubMedへ
  40. Umetsu M, Kanamori H, Murakami K, Shiga T, Yachi S, Takeyama M, Nishimoto Y, Tsujino I, Nakamura J, Yamamoto N, Nakata H, Ikeda S, Aikawa S, Hayashi H, Satokawa H, Okuno Y, Iwata E, Ogihara Y, Ikeda N, Kondo A, Iwai T, Yamada N, Ogawa T, Kobayashi T, Mo M, Yamashita Y: “Clinical Features Comparing Arterial Thrombosis and Venous Thromboembolism in Hospitalized Patients with COVID-19: Result from the CLOT-COVID Study”, Ann Vasc Dis,16(2):115-123(2023) PubMedへ
  41. Yachi S, Takeyama M, Nishimoto Y, Tsujino I, Nakamura J, Yamamoto N, Nakata H, Ikeda S, Umetsu M, Aikawa S, Hayashi H, Satokawa H, Okuno Y, Iwata E, Ogihara Y, Ikeda N, Kondo A, Iwai T, Yamada N, Ogawa T, Kobayashi T, Mo M, Yamashita Y, On Behalf Of The Clot-Covid Study Investigators: “Risk Factors and Impact on Outcomes of Thrombosis in Patients with COVID-19 in Japan: From the CLOT-COVID Study”, Ann Vasc Dis, 16(1):31-37(2023) PubMedへ
  42. Yamaguchi A, Saito Y, Narumi K, Furugen A, Takekuma Y, Shinagawa N, Shimizu Y, Dosaka-Akita H, Sugawara M, Kobayashi M: “Association between skin immune-related adverse events (irAEs) and multisystem irAEs during PD-1/PD-L1 inhibitor monotherapy”, J Cancer Res Clin Oncol, 149(4):1659-1666(2023). PubMedへ
  43. Yamashita Y, Yachi S, Takeyama M, Nishimoto Y, Tsujino I, Nakamura J, Yamamoto N, Nakata H, Ikeda S, Umetsu M, Aikawa S, Hayashi H, Satokawa H, Okuno Y, Iwata E, Ogihara Y, Ikeda N, Kondo A, Iwai T, Yamada N, Ogawa T, Kobayashi T, Mo M: “Significant Impact of Age on Mortality and Non-significant Impact of Age on Thrombosis and Major Bleeding in Patients with COVID-19: From the CLOT-COVID Study”, J Atheroscler Thromb. 30(6):624-635(2023) PubMedへ
  44. Yang Y, Kimura H, Yokota I, Makita H, Takimoto-Sato M, Matsumoto-Sasaki M, Matsumoto M, Oguma A, Abe Y, Takei N, Goudarzi H, Shimizu K, Suzuki M, Nishimura M, Konno S; Hi-CARAT investigators: “Applicable predictive factors extracted from peak flow trajectory for the prediction of asthma exacerbation”, Ann Allergy Asthma Immunol, S1081-1206(23)01464-3(2023) PubMedへ
  45. Wakazono N, Nagai K, Mizushima A, Maeda Y, Taniguchi N, Harada T, Satou E, Mae N, Furuya K: “ Febrile Reactions Associated with High IgG Antibody Titers after the Second and Third BNT162b2 Vaccinations in Japan”, Jpn J Infect Dis, 76(5):275-281(2023) PubMedへ
  46. Wu D, Jin Y, Xing Y, Abate MD, Abbasian M, Abbasi-Kangevari M, Abbasi-Kangevari Z, Abd-Allah F, Abdelmasseh M, Abdollahifar MA, Abdulah DM, Abedi A, Abedi V, Abidi H, Goudarzi H: “Global, regional, and national incidence of six major immune-mediated inflammatory diseases: findings from the global burden of disease study 2019”, EClinicalMedicine, 64:102193(2023) PubMedへ
  47. Zeng Y, Goudarzi H, Ait Bamai Y, Ketema RM, Roggeman M, den Ouden F, Gys C, Miyashita C, I to S, Konno S, Covaci A, Kishi R, Ikeda-Araki A: “Exposure to organophosphate flame retardants and plasticizers is positively associated with wheeze and FeNO and eosinophil levels among school-aged children: The Hokkaido study”, Environ Int, 181:108278(2023) PubMedへ
  48. 庄司哲明，品川尚文，高島雄太，菊池　創，池澤靖元，高階太一 今野　哲：「抗血小板薬・抗凝固薬内服患者における経気管支生検の有害事象の検討」，『気管支学』，45(2):89-97(2023)
症例報告
  1. Ishida Y, Suzuki M, Horii H, Nakamura J, Matsumoto M, Nakakubo S, Sato T, Tsujino I, Morita R, Abo D, Konno S: “An Adult Case of Unilateral Left Pulmonary Artery Agenesis Presenting with Hemoptysis”, Intern Med, 62(5):763-767(2023) PubMedへ
  2. Kurosawa S, Imafuku K, Nakakubo S, Iwasaki S, Teshima T, Goto H, Ujiie H: “Pseudotumor of the skin due to Mycobacterium genavense”, Int J Infect Dis,134:88-90(2023) PubMedへ
  3. Suzuki T, Tsujino I, Harabayashi W, Shima H, Nakamura J, Sato T, Suzuki M, Takeda Y, Konno S: “Pulmonary arterial hypertension in an 80-year-old man with long-term use of cyclophosphamide”, Respir Med Case Rep, 44:101867(2023) PubMedへ
  4. Suzuki T, Nakakubo S, Suzuki M, Konno S: “Visible Bronchial Obstruction after Hematopoietic Stem Cell Transplantation”, Intern Med, 62(21):3255-3256(2023) PubMedへ
  5. 石田有莉子，萩原　恵里，村上　陽亮，長澤 　遼，丹羽　 崇 ，奥田　良， 関根朗雅，小倉髙志：「カナマイシン筋注製剤による皮疹の既往がありアミカシン硫酸塩吸入用製剤でも皮疹をきたした肺 Mycobacterium avium complex 症の 1 例」，『Kekkaku』，98(5):155-158(2023)
総説・解説・その他
  1. Takashima Y, Oki M: “Endobronchial ultrasound with a guide sheath during bronchoscopy for peripheral pulmonary lesions”, Expert Rev Respir Med, 17(10):929-936(2023) PubMedへ
  2. 鈴木　雅：「かかりつけ医の役割：肺合併症管理（喘息・肺癌）」，『Medical Practice』，40(3):410-413(2023)
  3. 鈴木　雅：「COPD憎悪と肺炎は鑑別すべきか」，『呼吸器ジャーナル』，71(2):256-262(2023)
  4. 鈴木　雅：「COPDの画像的な病型分類」，「呼吸器内科」，44(5):603-609(2023)
著書
  1. 木村　孔一：「サルコイドーシス診療の手引き2020－診断と治療の進歩」，『呼吸器内科』，44(3):302-308(2023)
  2. 榊原　純，大泉聡史：「ブリグチニブ（アルンブリグ）」，『がん 最新の薬物療法　2023-2024』，南江堂，57-58(2023)