北海道大学大学院医学研究院 呼吸器内科学教室 北海道大学病院 呼吸器内科 Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University

研究業績

業績

H29 研究業績

原著論文
  1. Abe T, Murai S, Nasuhara Y, Shinohara N: “Characteristics of Medical Adverse Events/Near Misses Associated With Laparoscopic/Thoracoscopic Surgery: A Retrospective Study Based on the Japanese National Database of Medical Adverse Events”, J Patient Saf, doi: 10.1097/PTS.0000000000000422(2017) PubMedへ
  2. Aikawa T, Oyama-Manabe N, Naya M, Ohira H, Sugimoto A, Tsujino I, Obara M, Manabe O, Kudo K, Tsutsui H, Tamaki N: “Delayed contrast-enhanced computed tomography in patients with known or suspected cardiac sarcoidosis: A feasibility study”, Eur Radiol, 27(10):4054-4063(2017) PubMedへ
  3. Araki A, Mitsui T, Goudarzi H, Nakajima T, Miyashita C, Itoh S, Sasaki S, Cho K, Moriya K, Shinohara N, Nonomura K, Kishi R: “Prenatal di(2-ethylhexyl) phthalate exposure and disruption of adrenal androgens and glucocorticoids levels in cord blood: The Hokkaido Study”, Sci Total Environ,581-582:297-304(2017) PubMedへ
  4. Araki A, Miyashita C, Mitsui T, Goudarzi H, Mizutani F, Chisaki Y, Itoh S, Sasaki S, Cho K, Moriya K, Shinohara N, Nonomura K, Kishi R: “Prenatal organochlorine pesticide exposure and the disruption of steroids and reproductive hormones in cord blood: The Hokkaido study”, Environ Int, 110:1-13(2017) PubMedへ
  5. Asai N, Katsuda E, Hamanaka R, Kosaka K, Matsubara A, Nishimura M, Tanaka H, Yokoe N, Takahashi A, Yamaguchi E, Kubo A: “The ATS/ERS/JRS/ALAT statement "IPF by HRCT" could predict acute exacerbation of interstitial lung disease in non-small cell lung cancer”, Tumori, 103(1):60-65(2017) PubMedへ
  6. Asano F, Ishida T, Shinagawa N, Sukoh N, Anzai M, Kanazawa K, Tsuzuku A, Morita S: “Virtual bronchoscopic navigation without X-ray fluoroscopy to diagnose peripheral pulmonary lesions: a randomized trial”, BMC Pulm Med, 17(1):184(2017) PubMedへ
  7. Braimoh TS, Kobayashi S, Sata F, Sasaki S, Goudarzi H, Yila TA, Araki A, Miyashita C, Minakami H, Baba T, Sengoku K, Kishi R: “Association of prenatal passive smoking and metabolic gene polymorphisms with child growth from birth to 3 years of age in the Hokkaido Birth Cohort Study on Environment and Children's Health”, Sci Total Environ, 605-606:995-1002(2017) PubMedへ
  8. Goudarzi H, Araki A, Itoh S, Sasaki S, Miyashita C, Mitsui T, Nakazawa H,　Nonomura K, Kishi R: “The Association of Prenatal Exposure to Perfluorinated Chemicals with Glucocorticoid and Androgenic Hormones in Cord Blood Samples: The Hokkaido Study”, Environ Health Perspect, 125(1):111-118(2017) PubMedへ
  9. Goudarzi H, Miyashita C, Okada E, Kashino I, Chen CJ, Ito S, Araki A, Kobayashi S, Matsuura H, Kishi R: “Prenatal exposure to perfluoroalkyl acids and prevalence of infectious diseases up to 4years of age”, Environ Int, 104:132-138(2017) PubMedへ
  10. Hattori T, Konno S, Shijubo N, Ohmichi M, Yamaguchi T, Nishimura M: “ Resolution rate of pulmonary sarcoidosis and its related factors in a Japanese population”, Respirology, 22(8):1604-1608(2017) PubMedへ
  11. Ikezawa Y, Asahina H, Oizumi S, Watanabe M, Takamura K,Kawai Y, Yamada N, Harada T, Kinoshita I, Fujita Y, Miyauchi E, Ogi T, Amano T, Furuta M,　Sakakibara-Konishi J, Nishihara H, Dosaka-Akita H, Isobe H, Nishimura M; Hokkaido Lung Cancer Clinical Study Group: “A randomized phase II trial of erlotinib vs. S-1 as a third- or fourth-line therapy for patients with wild-type EGFR non-small cell lung cancer (HOT1002)”, Cancer Chemother Pharmacol, 80(5): 955-963(2017) PubMedへ
  12. Ikezawa Y, Sakakibara-Konishi J, Mizugaki H, Oizumi S, Nishimura M: “Inhibition of Notch and HIF enhances the antitumor effect of radiation in Notch expressing lung cancer”, Int J Clin Oncol, 22(1): 59-69(2017) PubMedへ
  13. Ikezawa Y, Shinagawa N, Sukoh N, Morimoto M, Kikuchi H, Watanabe M, Nakano K, Oizumi S, Nhisimura M: “Usefulness of endobronchial ultrasonography with a guide sheath and virtual bronchoscopic navigation for ground-glass opacity lesions”, Ann Thorac Surg, 103(2):470-475(2017) PubMedへ
  14. Kanazawa J, Masuko H, Yatagai Y, Sakamoto T, Yamada H, Kaneko Y, Kitazawa H, Iijima H, Naito T, Saito T, Noguchi E, Konno S, Nishimura M, Hirota T, Tamari M, Hizawa N: “Genetic association of the functional CDHR3 genotype with early-onset adult asthma in Japanese population”, Allergol Int, 66(4):563-567(2017) PubMedへ
  15. Kikuchi H, Sakakibara-Konishi J, Furuta M, Yokouchi H, Nishihara H, Yamazaki S, Uramoto H, Tanaka F, Harada M, Akie K, Sugaya F, Fujita Y, Takamura K, Kojima T, Harada T, Higuchi M, Honjo O, Minami Y, Watanabe N, Oizumi S, Suzuki H, Ishida T, Dosaka-Akita H, Isobe H, Munakata M, Nishimura M: “Expression of Notch1 and Numb in small cell lung cancer”, Oncotarget, 8(6):10348-10358(2017) PubMedへ
  16. Kimura H, Konno S, Makita H, Taniguchi N, Kimura H, Goudarzi H, Shimizu K, Suzuki M, Shijubo N, Shigehara K, Ono J, Izuhara K, Ito YM, Nishimura M: “Serum periostin is associated with body mass index and allergic rhinitis in healthy and asthmatic subjects”, Allergol Int, S1323-8930:30167-3(2017) PubMedへ
  17. Kimura H, Konno S, Nakamaru Y, Makita H, Taniguchi N, Shimizu K, Suzuki M, Ono J, Ohta S, Izuhara K, Nishimura M: “Sinus Computed Tomographic Findings in Adult Smokers and Nonsmokers with Asthma. Analysis of Clinical Indices and Biomarkers”, Ann Am Thorac Soc, 14(3): 332-341(2017) PubMedへ
  18. Kimura H, Suzuki M, Konno S, Shindou H, Shimizu T, Nagase T, Miyazaki T, Nishimura M: “Orchestrating role of apoptosis inhibitor of macrophage in the resolution of acute lung injury”, J Immunol, 199: 3870-3882(2017) PubMedへ
  19. Kitamura N, Seyama K, Inoue Y, Nagai K, Suzuki M, Moriyama H, Takada T, Tazawa R, Hirai T, Mishima M, Hayashida M, Hirose M, Arai T, Sugimoto C, Hattori N, Watanabe K, Tamada T, Akazawa K, Tanaka T, Nakata K: “Risk factors for stomatitis in patients with lymphangioleiomyomatosis during treatment with sirolimus: a multicenter investigator-initiated prospective study”, Pharmacoepidemiol Drug Saf, 26: 1182-1189(2017) PubMedへ
  20. Kobayashi Su, Sata F, Miyashita C, Miura R, Azumi K, Kobayashi Sa, Goudarzi H, Araki A , Ishizuka M, Todaka T, Kajiwara J, Hori T, Kishi R: “ Gender-specific association of exposure to non-dioxin-like polychlorinated biphenyls during pregnancy with methylation levels of H19 and long interspersed nuclear element-1 in cord blood in the Hokkaido study”, Toxicology, 390:135-145(2017) PubMedへ
  21. Kobayashi S, Sata F, Sasaki S, Braimoh TS, Araki A, Miyashita C, Goudarzi H, Kobayashi S, Kishi R: “Modification of adverse health effects of maternal active and passive smoking by genetic susceptibility: Dose-dependent association of plasma cotinine with infant birth size among Japanese women-The Hokkaido Study”, Reprod Toxicol, 74:94-103(2017) PubMedへ
  22. Kobayashi S, Azumi K, Goudarzi H, Araki A, Miyashita C, Kobayashi S, Itoh S, Sasaki S, Ishizuka M, Nakazawa H, Ikeno T, Kishi R: “Effects of prenatal perfluoroalkyl acid exposure on cord blood IGF2/H19 methylation and ponderal index: The Hokkaido Study”, J Expo Sci Environ Epidemiol, 27(3):251-259(2017) PubMedへ
  23. Kobayashi S, Sata F, Miyashita C, Sasaki S, Ban S, Araki A, Goudarzi H, Kajiwara J, Todaka T, Kishi R: “Dioxin-metabolizing genes in relation to effects of prenatal dioxin levels and reduced birth size: The Hokkaido study”, Reprod Toxicol, 67:111-116(2017) PubMedへ
  24. Konno S, Makita H, Suzuki M, Shimizu K, Kimura H, Kimura H, Nishimura M: “Acute bronchodilator responses to β2-agonist and anticholinergic agent in COPD: Their different associations with exacerbation”, Respir Med, 127:14-20(2017) PubMedへ
  25. Minatoya M, Itoh S, Miyashita C, Araki A, Sasaki S, Miura R, Goudarzi H, Iwasaki Y, Kishi R: “Association of prenatal exposure to perfluoroalkyl substances with cord blood adipokines and birth size: The Hokkaido Study on environment and children's health”, Environ Res, 156:175-182(2017) PubMedへ
  26. Morikawa N, Inoue A, Sugawara S, Maemondo M, Harada T, Harada M, Fujita Y, Katoh T, Yokouchi H, Watanabe H, Usui K, Suzuki T, Sakakibara-Konishi J, Nagai H, Kanbe M, Nukiwa T: “Randomized phase II study of carboplatin plus irinotecan versus carboplatin plus amrubicin in patients with chemo-naïve extensive-stage small-cell lung cancer: North Japan Lung Cancer Study Group (NJLCG) 0901”, Lung Cancer, 111:38-42(2017) PubMedへ
  27. Nagaoka K, Yanagihara K, Harada Y, Yamada K, Migiyama Y, Morinaga Y, Izumikawa K, Kohno S: “Quantitative detection of periodontopathic bacteria in lower respiratory tract specimens by real-time PCR”, J Infect Chemother, 23(2):69-73(2017) PubMedへ
  28. Nagaoka K, Yanagihara K, Morinaga Y, Kohno S: “Detection of Fusobacterium nucleatum in two cases of empyema and lung abscess using paromomycin-vancomycin supplemented Brucella HK agar”, Anaerobe, 43:99-101(2017) PubMedへ
  29. Nagaoka K, Yanagihara K, Morinaga Y, Kurosaka Y, Hoshino K, Kohno S: “In vivo antianaerobe activity of DS-8587, a new fluoroquinolone, against Fusobacterium necrophorum in a mouse model”, J Infect Chemother, 23(3):131-135(2017) PubMedへ
  30. Nakamura H, Kato M, Nakaya T, Kono M, Tanimura S, Sato T, Fujieda Y, Oku K, Ohira H, Bohgaki T, Yasuda S, Tsujino I, Nishimura M, Atsumi T: “Decreased haptoglobin levels inversely correlated with pulmonary artery pressure in patients with pulmonary arterial hypertension: A cross-sectional study”, Medicine (Baltimore), 96 (43): e8349(2017) PubMedへ
  31. Noguchi A, Kato M, Kono M, Ohmura K, Ohira H, Tsujino I ,Oyama-Manabe N, Oku K, Bohgaki T, Horita T, Yasuda S, Nishimura M, Atsumi T: “Bi-ventricular interplay in patients with systemic sclerosis-associated pulmonary arterial hypertension: Detection by cardiac magnetic resonance”, Mod Rheumatol, 27 (3): 481-488(2017) PubMedへ
  32. Nokihara H, Yamamoto N, Yamada Y, Honda K, Asahina H, Tamura Y, Hozak RR, Gao L, Suzukawa K, Enatsu S, Tamura T: “A phase 1 study of ramucirumab in Japanese patients with advanced solid tumors”, Jpn J Clin Oncol, 47(4): 298-305(2017) PubMedへ
  33. Ohira H, Mc Ardle B, deKemp RA, Nery PB, Juneau D, Renaud JM, Klein R, Clarkin O, MacDonald K, Leung E,Nair G, Beanlands RS, Birnie D: “Inter-and Intra-observer agreement of FDG-PET/CT image interpretation in patients referred for assessment of Cardiac Sarcoidosis”, J Nucl Med, 58(8): 1324-1329(2017) PubMedへ
  34. Sakakibara-Konishi J, Ikezawa Y, Oizumi S, Kikuchi J, Kikuchi E, Mizugaki H, Kinoshita I, Dosaka-Akita H, Nishimura M: “Combined antitumor effect of γ-secretase inhibitor and ABT-737 in Notch-expressing non-small cell lung cancer”, Int J Clin Oncol, 22(2):257-268(2017) PubMedへ
  35. Santiwarangkool S, Akita H, Kusumoto K, Kimura H, Suzuki M, Nishimura M, Sato Y, Harashima H: “PEGylation of the GALA prptide enhances the lung-targeting activity of nanocarriers that contain encapsulated siRNA”, J Pharm Sci , 106: 2420-2427(2017) PubMedへ
  36. Sato T, Tsujino I, Ohira H, Oyama-Manabe N, Ito YM, Takashina C, Watanabe T, Nishimura M: “Accuracy of echocardiographic indices for serial monitoring of right ventricular systolic function in patients with precapillary pulmonary hypertension”, PLoS One, 12(11): e0187806 (2017) PubMedへ
  37. Shimizu K, Tsujino I, Sato T, Sugimoto A, Nakaya T, Watanabe T, Ohira H, Ito Y, Nishimura M: “Performance of computed tomography-derived pulmonary vasculature metrics in the diagnosis and haemodynamic assessment of pulmonary arterial hypertension”, Eur J Radiol, 96: 31-38(2017) PubMedへ
  38. Suzuki M, Sze MA, Campbell JD, Brothers JF, Lenburg ME, McDonough JE, Elliott WM, Cooper JD, Spira A, Hogg JC: “The cellular and molecular determinants of emphysematous destruction in COPD”, Sci Rep, 7(1):9562(2017) PubMedへ
  39. Tanabe N, Vasilescu DM, McDonough JE, Kinose D, Suzuki M, Cooper JD, Paré PD, Hogg JC: “MicroCT comparison of preterminal bronchioles in centrilobular and panlobular emphysema”, Am J Respir Crit Care Med, 195(5): 630-638(2017) PubMedへ
  40. Yokoe N, Katsuda E, Kosaka K, Hamanaka R, Matsubara A, Nishimura M, Tanaka H, Asai N, Takahashi A, Kawamura T, Ishiguchi T, Yamaguchi E, Kubo A : “Interstitial Lung Disease after Pleurodesis for Malignant Pleural Effusion”, Intern Med, 56(14):1791-1797(2017) PubMedへ
  41. Yokouchi H, Nishihara H, Harada T, Ishida T, Yamazaki S, Kikuchi H, Oizumi, S, Uramoto H, Tanaka F, Harada M, Akie k, Sugaya F, Fujita Y, Takamura K, Kojima T, Higuchi M, Honjo O, MinamiY, Watanabe N, Goto A, Suzuki H, Dosaka- Akita H, Isobe H, Nishimura M, Munakata M: “Immunohistochemical profiling of receptor tyrosine kinases, MED12, and TGF-βRII of surgically resected small cell lung cancer, and the potential of c-kit as a prognostic marker”, Oncotarget, 8(24):39711-39726(2017) PubMedへ
  42. 飯島弘晃，増子裕典，金子美子，金澤　潤，北沢晴奈，谷田貝洋平，山田英恵，坂本　透，今野　哲，西村正治，檜澤伸之：「ダニ抗原感作におけるTSLP遺伝子と環境ダニ抗原量との交互作用に関する検討」，『日本職業・環境アレルギー学会雑誌』，24(2)：25-34(2017)
症例報告
  1. 黒木　茜，本多敏朗，松本　諭，藤原　豊，八巻稔明，鈴木　昭：「無痛性甲状腺炎と糖尿病ケトアシドーシスを契機に先端巨大症と診断され、経過中に下垂体卒中をきたした１例」，『糖尿病』，60(12)：813-819(2017)
  2. 本村文宏，品川尚文，田中明彦，泉　寛志，秋江研志，楠堂晋一，櫻庭　幹，深澤雄一郎：「気管支鏡が有用であった肺の唾液腺癌の2例」，『市立札幌病院医誌』，76(2):43-47(2017)
総説・解説・その他
  1. Birnie D , Ohira H, Beanlands R: “Reply: Using and Interpreting 18F-FDG PET/CT Images in Patients Referred for Assessment of Cardiac Sarcoidosis: The Devil Is in the Details”, J Nucl Med, 58 (12):2040(2017) PubMedへ
  2. Kishi R, Araki A , Minatoya M, Hanaoka T, Miyashita C, Itoh S, Kobayashi S, Ait Bamai Y, Yamazaki K, Miura R, Tamura N, Goudarzi H: “The Hokkaido Birth Cohort Study on Environment and Children's Health: cohort profile-updated 2017”, Environ Health Prev Med, 22:46(2017) PubMedへ
  3. Ohira H, Yoshinaga K, Manabe O, Oyama-Manabe N, Tsujino I, Nishimura M, Tamaki N: “Clinical Application of 18F-fluorodeoxyglucose PET and LGE CMR inCardiac Sarcoidosis”, Ann Nucl Cardiol, 3(1):125-130(2017) PubMedへ
  4. Sato T, Ohira H, Tsujino I: “Representative Chest Auscultation Findings in Pulmonary Hypertension: Phonocardiograms and Sound Clips”, Ann Am Thorac Soc, 14 (5): e1-e3(2017) PubMedへ
  5. Vogelmeier CF, Criner GJ, Martinez FJ, Anzueto Ā, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DM, Lopez Varela MV, Nishimura M, Roche N, Rodriguez-Roisin R, Sin DD, Singh D, Stockley R, Vestbo J, Wedzicha JA, Agusti A: “Global Strategy for the Diagnosis,Management,and Prevention of Chronic Obstructive Lung Disease 2017 Report．GOLD Executive Summary”, Am J Respir Crit Care Med, 195(5): 557-582(2017) PubMedへ
  6. Vogelmeier CF, Criner GJ, Martinez FJ, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DM, L .A Nspez Varela MV, Nishimura M, Roche N, Rodriguez-Roisin R, Sin DD, Singh D, Stockley R, Vestbo J, Wedzicha JA, Agusti A: “Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary”, Eur Respir J, 49(3): 1700214 (2017) PubMedへ
  7. Vogelmeier CF, Criner GJ, Martinez FJ, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DM, L .A Nspez Varela MV, Nishimura M, Roche N, Rodriguez-Roisin R, Sin DD, Singh D, Stockley R, Vestbo J, Wedzicha JA, Agusti A: “Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary”, Respirology, 22(3): 575-601 (2017) PubMedへ
  8. 朝比奈肇：「話題. 第4世代EGFR-TKI：EAI045」，『腫瘍内科』，19(5)：582-588(2017)
  9. 池澤靖元，品川尚文：「気管支鏡検査」，『呼吸器ジャーナル 若手医師のための呼吸器診療スキルアップー苦手意識を克服しよう』，65(2)：244-251(2017)
  10. 木村孔一，今野哲：「副鼻腔CT、バイオマーカーからみた気管支喘息における上下気道の連関」，『アレルギーの臨床』，12月増刊号：57-62(2017)
  11. 今野　哲：「粉じんばく露回避前後の経過を観察しえた超硬合金肺の1例」，『産業医学ジャーナル』，40(2)：15-19(2017)
  12. 今野　哲：「肥満と気管支喘息」，『 アレルギー』，66(7)：919-922(2017)
  13. 今野　哲：「喘息重症化因子 3.肥満 」，『最新医学』，72(7)：44-49(2017)
  14. 榊原　純，大泉聡史：「非小細胞肺がんに対する複合免疫療法の可能性」，『腫瘍内科』，19(5)：543-548(2017)
  15. 清水薫子，西村正治：「COPDの重症度は画像所見で判定できるのか？呼吸器画像診断－エキスパートの視点」，『呼吸器ジャール』，65(1)：122-128(2017)
  16. 清水薫子，西村正治：「循環器疾患患者における呼吸機能検査の重要性」，『CARDIAC PRACTICE』，28(1)：27-32(2017)
  17. 清水薫子，西村正治：「5.診断(2)　呼吸機能」，『喘息・COPDのオーバーラップ症候群(Asthma and COPD Overlap Syndrome: ACOS)の診断と治療の手引き』，53-55(2017)
  18. 南須原康行：「特集　医薬品の禁忌・適応外使用、5．医療安全管理者が求める安全性の確立していない医薬品の使用について」，『医薬ジャーナル53：2485-2490(2017)
  19. 南須原康行：「特集　これまでの医療安全、これからの医療安全、４．医療安全に関する制度の変遷」，『患者安全推進ジャーナル』，50： 28-32(2017)
  20. 西村正治：「COPD」，『毎日新聞』，3月10日発刊(20017)
  21. 西村正治：「COPD(慢性閉塞性肺疾患)」，『聖教新聞』，7月9日発刊(2017)
  22. 西村正治：「ウエスト　呼吸生理学入門：正常肺編　第2版」，『呼吸器ジャーナル』，65(3)：497(2017)
  23. 西村正治：「ヒトは何故息切れを感じるのか」，『毎日新聞』，8月5日発刊(2017)
  24. 西村正治：「健康日本21(第二次)でCOPDをとりあげた理由」，『複十字』，376:14-15(2017)
  25. 西村正治：「多機種の協働によって成功した北海道COPDコホート研究」，『日本呼吸ケア・リハビリテーション学会誌』，27(1)：11-14(2017)
  26. 服部健史，今野哲：「１．重症喘息患者のフェノタイプとエンドタイプ 」，『アレルギー・免疫』，24(12)：48-53(1618-1623)(2017)
  27. 福居嘉信，今野　哲：「炎症と気道過敏性」，『BIO Clinica』，6(1)：33-37(2017)
  28. 渡部　拓：「改めて知りたい血糖値の話」，『ontona』，8月30日発刊(2017)
著書
  1. 木村孔一，今野　哲：「重症喘息の管理・治療」，『呼吸器疾患診断治療アプローチ・気管支喘息』，(中山書店)，234-239(2017)
  2. 品川尚文：「第3章　診断　気管支鏡検査」，『最新医学別冊　診断と治療のABC 123 呼吸器腫瘍』，【最新医学社・大阪・中西洋一　編】，73-79(2017)
  3. 品川尚文：「第3章　診断　気管支鏡」，『最新医学別冊　新しい診断と治療のABC34 肺がん5 改訂第2版』，【最新医学社・大阪・阿部庄作　編】，85-92(2017)
  4. 品川尚文：「気管支鏡の基本手技」，『気管支鏡ベストテクニック 改訂2版』，【中外医学社・東京・浅野文祐,宮澤輝臣　編】，1-16(2017)
  5. 清水薫子，西村正治：「気管支喘息患者の肺拡散能力」，『呼吸器疾患診断治療アプローチ　気管支喘息』，139-141(2017)
  6. 西村正治：「慢性閉塞性肺疾患(COPD)」，『今日の治療指針』，59:294-296(2017)
  7. 西村正治：「呼吸困難」，『内科学』，第11版:：113-116(2017)