北海道大学大学院医学研究院 呼吸器内科学教室 北海道大学病院 呼吸器内科 Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University

研究業績

研究業績一覧

業績

原著論文
  1. Kato M, Kataoka H, Odani T, Fujieda Y, Otomo K, Oku K, Horita T, Yasuda S, Atsumi T, Ohira H, Tsujino I, Nishimura M，Koike T．：“The Short-term role of corticosteroid therapy for pulmonary arterial hypertension associated with connective tissue diseases: report of five cases and a literature review”，Lupus，20：1047-1056(2011) PubMedへ
  2. Asahina H, Oizumi S, Inoue A, Kinoshita I, Ishida T, Fujita Y, Sukoh N, Harada M, Maemondo M, Saijo Y, Dosaka-Akita H, Isobe H, Nukiwa T, Nishimura M;behalf of the Hokkaido Lung Cancer Clinical Study Group．：“Phase II Study of gefitinib readministration in patients with advanced non-small cell lung cancer and previous response to gefitinib”，Oncology，79：423-429(2011) PubMedへ
  3. Kikuchi J, Kinoshita I, Shimizu Y, Kikuchi E, Takeda K, Aburatani H, Oizumi S, Konishi J, Kaga K, Matsuno Y, Birref MJ, Nishimura M, Dosaka-Akita H．：“Minichromosome maintenance (MCM) protein 4 as a marker for proliferation and its clinical and clinicopathological significance in non-small cell lung cancer”Lung Cancer，72 ：229-237(2011) PubMedへ
  4. Satoh H, Inoue A, Kobayashi K, Maemondo M, Oizumi S, Isobe H, Gemma A, Saijo Y, Yoshizawa H, Hagiwara K, Nukiwa T．：“Low-Dose Gefitinib Treatment for Patients with Advanced Non-small Cell Lung Cancer Harboring Sensitive Epidermal Growth Factor Receptor Mutations”，J Thorac Oncol，6(8)：1413-1417(2011) PubMedへ
  5. Shimizu K, Hasegawa M, Makita H, Nasuhara Y, Konno S, Nishimura M．：“Comparison of airway remodelling assessed by computed tomography in asthma and COPD“，Respir Med，105(9)：1275-1283(2011) PubMedへ
  6. Akie K, Oizumi S, Ogura S, Shinagawa N, Kikuchi E, Fukumoto S, Harada M, Kinoshita I, Kojima T, Harada T, Fujita Y, Ohsaki Y, Dosaka-Akita H, Isobe H, Nishimura M．：“Phase II Study of Irinotecan plus S-1 Combination for Previously Untreated Advanced Non-Small Cell Lung Cancer : Hokkaido Lung Cancer Clinical Study Group Trial (HOT) 0601“，Oncology，81(2)：84-90(2011) PubMedへ
  7. Fukutomi Y, Taniguchi M, Nakmura H, Konno S, Nishimura M, Kawagishi Y, Okada C, Tanimoto Y, Takahashi K, Akasawa A, Akiyama K．：“Association between Body Mass Index and Asthma among Japanese Adults : Risk within the Normal Weight Range“，Int Arch Allergy Immunol，157(3)：281-287(2011) PubMedへ
  8. Ishida T, Asano F, Yamazaki K, Shinagawa N, Oizumi S, Moriya H, Munakata M, Nishimura M; Virtual Navigation in Japan Trial Grup：“Virtual bronchoscopic navigation combined with endobronchial ultrasound to diagnose small peripheral pulmonary lesions: a randomised trial“，Thorax，66(12)：1072-1077(2011) PubMedへ
  9. Konno S, Kurokawa M, Ueda T, Nishimura M, Huang SK．：“Role of osteopontin, a multifunctional protein, in allergy and ashtma“，Clin Exp Allergy，41(10)：1360-1366(2011) PubMedへ
  10. Konno S, Makita H, Hasegawa M, Nasuhara Y, Nagai K, Betsuyaku T, Hizawa N, Nishimura M．：“Beta2-adrenergic receptor polymorphisms as a determinant of preferential bronchodilator responses to β2-agonist and anticholinergic agents in Japanese patients with chronic obstructive pulmonary disease“，Pharmacogenet Genomics，21(11)：687-693(2011) PubMedへ
  11. McDonough J, Yuan R, Suzuki M, Seyednejad N, Elliott W, Sanchez P, Wright A, Gefter W, Litzky L, Coxson H, Pare P, Sin D, Pierce R, Woods J, McWilliams A, Mayo J, Lam S, Cooper J, Hogg J．：“Small-airway obstruction and emphesema in chronic obstructive pulmonary disease“，N Engl J Med，351：1567-1575(2011) PubMedへ
  12. Morita S, Oizumi S, Minami H, Kitagawa K, Komatsu Y, Fujiwara Y, Inada M, Yuki S, Kiyota N, Mitsuma S, Sawaki M, Tanii H, Kimura J, Ando Y．：“Phase I dose-escalating study of panobinostat (LBH589) Administered intravenously to Japanese patientes with advanced solid tumors“，Invest New Drugs，30(5)：1950-1957(2011) PubMedへ
  13. Ohira H, Tsujino I, Yoshinaga K．：“18F-Fluoro-2-deoxyglucose positron emission tomography in cardiac sarcoidosis“，Eur J Nucl Med Mol Imaging，38(9)：1773-1783(2011) PubMedへ
  14. Onodera Y, Nishioka N, Yasuda K, Fujima N, Torres M, Kamishima T, Ooyama N, Onimaru R, Terae S, Oizumi S, Nishimura M, Shirato H．：“Relationship between diseased lung tissues on computed tomography and motion of fiducial marker near lung cancer“，Int J Radiat Oncol Biol Phys，79(5)：1408-1413(2011) PubMedへ
  15. Sato T, Kato T, Kamamura K, Hashimoto S, Shishido T, Mano A, Oda N, Takahashi A, Ishibashi-Ueda H, Nakatani T, Asakura M, Kanzaki H, Hashimura K, Kitakaze M．：“Utility of left ventricular systolic torsion derived from 2-dimensional speckle-tracking echocardiography in monitoring acute cellular rejection in heart transplant recipients“，J Heart Lung Transplant,30(5)：536-543(2011) PubMedへ
  16. Sakakibara-Konishi J, Oizumi S, Kinoshita I, Shinagawa N, Kikuchi J, Kato M, Inoue T, Katoh N, Onimaru R, Shirato H, Dosaka-Akita H, Nishimura M．：“Phase I study of concurrent real-time tumortracking thoracic radiation therapy with paclitaxel and carboplatin in locally advanced non-small cell lung cancer“，Lung Cancer，72(2)：248-252(2011) PubMedへ
  17. Sekine I, Kubota K, Tamura Y, Asahsina H, Yamada K, Horinouchi H, Nokihara H, Yamamoto N, Tamura T．：“Innovator and generic cisplatin formulations: comparison of renal toxicity“，Cancer Sci，102(1)：162-165(2011) PubMedへ
  18. Silverman EK, Vestbo J, Agusti A, Anderson W, Bakke PS, Barnes KC, Barr RG, Bleecker ER, Boezen HM, Burkart KM, Celli BR, Cho MH, Cookson WO, Croxton T, Daley D, DeMeo DL, Gan W, Garcia-Aymerich J, Hall IP, Hansel NN, Hersh CP, Kalsheker N, Kiley JP, Kim WJ, Lambrechts D, Lee SD, Litonjua AA, Lomas DA, London SJ, Nishimura M, Nordestgaard BG, ODonnell CJ, Postma DS, Puhan MA, Tesfaigzi Y, Tobin MD, Vogelmeier C, Wilk JB, Wouters E, Young RP, Ziegler-Heitbrock L, MacNee W, Grapo JD．：“Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report“，COPD，8(2)：121-135(2011) PubMedへ
症例報告
  1. 谷口菜津子，今野　哲，南須原康行，松野吉宏，岡　輝明，西村正治：「結節性硬化症病変を伴わないmultifocal micronodular pneumocyte hyperplasia の1例」，『日本呼吸器学会雑誌』，49(5)：355-359(2011)
  2. Ohira H，Tsujino I, Sato T, Yoshinaga K, Manabe O, Oyama N,Nishimura M．：“Early detection of cardiac sarcoid lesions with 18F-fluoro-2-deoxyglucose positron emission tomography”，Intern Med，50：1207-1209(2011) PubMedへ
  3. 佐藤隆博，辻野一三，大平　洋，山田安寿香，後藤知紗，渡部　拓，西村正治：「門脈肺高血圧症の急性増悪にAmbrisentanとTadalafilのCombination Therapyが著効した1例」，『THERAPEUTIC RESEARCH』，32(10)：1214-1216(2011)
総説・解説
  1. 吉田貴之，今野　哲，西村正治：「講座　稀な肺疾患　重複大動脈弓」，『呼吸』，30(1)：53-56(2011)
  2. 猪又崇志，西村正治：「COPD早期介入と最新治療」，『Vita』，28(2)：38-43(2011)
  3. 西村正治：「呼吸器疾患の70年を振り返る　第6回　慢性閉塞性肺疾患）COPD）－疾患概念の変遷を中心として－」，『日本胸部臨床』，70(6)：600-609(2011)
  4. 清水薫子，西村正治：「特集　COPDの薬物療法の新展開　吸入式気管支拡張薬の利点と欠点」，『THE LUNG perspectives』，19(2)：137-141(2011)
  5. 朝比奈　肇，田村友秀：「特集　肺癌の薬物療法；最新治療と新たな試み　非小細胞肺癌　初回治療と二次治療意向；ガイドラインを含めて」，『Pharma Medica』，29(6)：9-14(2011)
  6. Koiwa H，Tsujino I, Ikeda D, Ohira H, Tanino M, Nishimura M．：“An autopsy case of pulmonary venoocclusive disease refractory to imatinib”，Eur Repir J，37(4)：968-970(2011) PubMedへ
  7. 大泉聡史：「気管支鏡の所見および気管支鏡検査」，『呼吸器研修ノート』，281-293(2011)
  8. 大泉聡史：「PS不良例の化学療法の適応を教えてください。また工夫していることがあれば教えて下さい」，『肺癌診療Q＆A一つ上を行く診療の実践』，271-274(2011)
  9. 今野　哲：「共通分子，遺伝子多型の観点から」，『アレルギーの臨床』，31(7)：40-44(2011)
  10. 清水薫子，西村正治：「大規模臨床試験から得られたCOPD薬物療法のエビデンス－TORCH試験，UPLIFT試験，PEACE試験を中心に－」，『日本臨床』，69(10)：1815-1820(2011)
  11. 牧田比呂仁，西村正治：「COPD診療の地域連携の重要性とすすめかた　北海道COPDコホート研究」，『Medical Practice』，28(3)：476-479(2011)
学会賞
  1. 服部健史：気道上皮における自然免疫と獲得免疫の働き：喘息におけるIL-1ファミリーの役割，Banyu Fellowship Program
  2. 服部健史：喘息における上皮成長因子（EGF)の役割の検討，Banyu Fellowship Program
  3. 服部健史：肺サルコイドーシスの自然経過に関する検討，サルコイドーシス学会学術奨励賞
  4. Makita H，Taniguchi N，Konno S，Fuke K，Nagai K，Nasuhara Y，Nishimura M; Hokkaido COPD cohort study grup：Predictors of Exacerbation in Japanese patients with chronic obstructive pulmonary disease，APSR 2011-poster Honorable Award
  5. 清水薫子、長谷川　大、牧田比呂仁、南須原康行、今野　哲、西村正治：COPD患者における肺機能と気道内腔面積の関係－肺気量変化と気管支拡張薬効果からみた検討－，第20回Pneumo Forum賞